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What is the GANODERIC ACID A ?
GANODERIC ACID A is , while it's Molecular Formula is C30H42O7. Ganoderic Acid A, is a new lanostanoid triterpene extracted from the fruit bodies of Ganoderma Lucidum mushroom. these compounds are shown to possess many therapeutic properties. They can be used as anti-virus, anti-inflammation, anti-tumor, immunity-promoting, anti-diabetic, etc.
What is the CAS number for GANODERIC ACID A ?
The CAS number of GANODERIC ACID A is 81907-62-2.
More information of GANODERIC ACID A 81907-62-2 are:
|
Synonyms |
Ganodericacid A;(7beta,15alpha,25R)-7,15-dihydroxy-3,11,23-trioxolanost-8-en-26-oic acid;Lanost-8-en-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7β,15α,25R)-; |
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CAS?Number |
81907-62-2 |
|
Molecular Formula |
C30H42O7 |
|
Molecular Weight |
514.65 |
|
Density |
1.22 g/cm3 |
|
Melting Point |
118～123℃ |
|
Boiling Point |
690.1 °C at 760 mmHg |
|
Flash Point |
385.1 °C |
|
HS CODE |
29189900 |
|
PSA |
128.97000 |
|
LogP |
4.05160 |
|
Pka |
4.78±0.23(Predicted) |
What is GANODERIC ACID A (81907-62-2) used for?
Ganoderic acid A is a triterpene that has been found in Ganoderma and has diverse biological activities. It reduces cell viability, expression of superoxide dismutase 1 (SOD1), SOD2, and SOD3, and production of reactive oxygen species (ROS) in PC3 prostate cancer cells. Ganoderic acid A (2-100 μg/ml) reduces hypoxia-induced apoptosis in H9c2 cardiomyocytes. It inhibits LPS-induced activation of NF-κB, release of TNF-α, IL-1β, and IL-6, and mitochondrial activity in primary mouse cortical microglia. Ganoderic acid A (20 and 40 mg/kg) reduces lung myeloperoxidase (MPO) activity, neutrophil infiltration, and NF-κB signaling, as well as bronchoalveolar lavage fluid (BALF) levels of TNF-α, IL-1β, and IL-6 in a mouse model of LPS-induced lung injury. It also reduces weight gain and hepatic lipid accumulation and improves insulin sensitivity in a mouse model of high-fat diet-induced obesity.
InChI:InChI=1/C30H44O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21,23,32,35H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21+,23+,28+,29-,30+/m1/s1
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