(2-methyl-2-phenyl-propyl) acetate

  • CAS No.:18755-52-7
  • Purity:99%
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Manufacturer supply high quality (2-methyl-2-phenyl-propyl) acetate 18755-52-7 with GMP standards

  • Molecular Formula:C12H16 O2
  • Molecular Weight:192.258
  • Vapor Pressure:0.0151mmHg at 25°C 
  • Boiling Point:256.8°Cat760mmHg 
  • Flash Point:100.8°C 
  • PSA:26.30000 
  • Density:0.998g/cm3 
  • LogP:2.52730 

(2-methyl-2-phenyl-propyl) acetate(Cas 18755-52-7) Usage

General Description

(2-methyl-2-phenyl-propyl) acetate, also known as "homosalate," is an organic compound commonly used as an ingredient in sunscreen and other cosmetic products. It is an ester formed from the condensation of acetic acid and (2-methyl-2-phenyl-propyl) alcohol, and it provides UVB protection by absorbing and dissipating harmful rays from the sun. Homosalate is generally well-tolerated by most individuals and is considered safe for use in personal care products when used in concentrations of up to 15%. However, there have been some concerns raised about its potential to disrupt hormone function or cause skin irritation in sensitive individuals, so it is important to consider these factors when using products containing this chemical.

InChI:InChI=1/C12H16O2/c1-10(13)14-9-12(2,3)11-7-5-4-6-8-11/h4-8H,9H2,1-3H3

18755-52-7 Relevant articles

Impact of Oxidation State on Reactivity and Selectivity Differences between Nickel(III) and Nickel(IV) Alkyl Complexes

Roberts, Courtney C.,Camasso, Nicole M.,Bowes, Eric G.,Sanford, Melanie S.

, p. 9104 - 9108 (2019)

Described is a systematic comparison of ...

Regio-selective synthesis of key intermediates of fexofenadine

Kumar, Anil,Bhashkar, Bhuwan,Kumar, Harish,Singh, Gurpreet

, p. 2285 - 2287 (2015/12/19)

The present work is focused on improved ...

The synthesis of fexofenadine

Ronggeng, Wang,Yougui, Zhao,Guanchao, Zhang

, p. 2149 - 2155 (2013/06/05)

This work proposes a new simple route fo...

Synthesis of [2H5]-ebastine fumarate and [ 2H5]-hydroxyebastine

Yu, Zhoujie,Wang, Wei,Chen, Liqin

experimental part, p. 352 - 356 (2012/06/01)

This study describes the synthesis of de...

18755-52-7 Process route

neophyl chloride
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neophyl chloride

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potassium acetate

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Conditions
Conditions Yield
In 1-methyl-pyrrolidin-2-one; at 160 - 165 ℃;
80%
With 1-methyl-pyrrolidin-2-one; at 200 ℃;
2-methyl-2-phenyl-propan-1-ol
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(2-acetoxy-1,1-dimethylethyl)benzene
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Conditions
Conditions Yield
With pyridine; acetyl chloride; In dichloromethane; at 20 ℃;

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