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What is the Baricitinib ?

Baricitinib is , while it's Molecular Formula is C16H17N7O2S. Baricitinib is a JAK1 and JAK2 inhibitor and have been used as a promising treatment for rheumatoid arthritis.

What is the CAS number for Baricitinib ?

The CAS number of Baricitinib is 1187594-09-7.

More information of Baricitinib 1187594-09-7 are:

What is Baricitinib (1187594-09-7) used for?

Baricitinib (1187594-09-7), approved by the FDA for two inflammatory disorders, rheumatoid arthritis and alopecia areata, selectively inhibits Janus kinase 1 (IC50?= 5.9 nM) and 2 (5.7 nM), over 3 (0.56 μM).1?It thereby blocks JAK/STAT signaling, reducing cytokine release and suppressing the innate and adaptive immune systems.1,2?Was recently shown to significantly improve COVID-19 symptoms in a preliminary human trial, presumably through suppression of the cytokine release syndrome (“cytokine storm”) induced by SARS-CoV-2 infection.3

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